ParkinsonDiseaseisacomprehensiveintroductiontothebiologyandclinicalfeaturesofParkinsondisease(PD).Thisbookisaimedatcliniciansintraining,generalneurologistsseekingausefulguidetoPD,andscientistsseekinganoverviewofclinicalaspectsofPD.TopicscoveredincludenosologyofPD,PDepidemiology,pathologyandpathophysiologyofPD,andtheoriesofPDpathogenesis.Clinicalfeatures,includingthemanynon-motorfeatures,naturalhistoryofdiseaseprogression,clinicalpharmacology,andmanagementofPDreceivecoverage.ImportantthemesareheterogeneityofPD,themulti-focalnatureofPDpathology,thediversityofclinicalfeatures,dopaminergicsignalingandtheimpactsofdopaminergicdeficiency,theimportanceofnon-motorfeatures,limitationsofexistingtreatmentmodalities,andthenecessityofapproachingPDasamulti-systemdisorder.ThedescriptionanddiscussionofthemanyaspectsofParkinsondisease(PD)isdoggedbythefactthatPDisanambiguousconcept.Thisbookintendstobeausefuloverview,bridgingthegapbetweengeneraltextbooksandspecifictopicalreviews.
